Articles:

Clonidine

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Intestinal negative side effects have actually most commonly included dry mouth (30 %) and also irregularity (15 %), abdominal pain, anorexia, nausea, vomiting, looseness of the bowels (1 %), parotitis, pseudo-obstruction (consisting of colonic pseudo-obstruction), as well as salivary glandular pain. Nausea or vomiting (13.2 %) and vomiting (10.5 %) have been reported with epidural clonidine. [Ref]



Genitourinary adverse effects have actually included impotence in male clients (24 %), retrograde as well as delayed climaxing, and also a lack of ability to accomplish orgasm in female individuals. [Ref]



A 66-year-old female with a record of psoriasis in remission established erythematous, scabby cavity enducing plaques on the extensor surface areas of her lower arms within three days after starting clonidine treatment for command of flushing. The author of this case record believed that clonidine might cause a fall in intracellular cAMP, bring about epidermal cell spreading, and, in many cases, a psoriasiform eruption. [Ref]



Dermatologic reactions have been reported in 10 % to 38 % of people that use transdermal clonidine. These responses consist of psoriasis exacerbations, local dermatitis and/or coloring, alopecia, angioneurotic edema, hives, urticaria, pruritus, and also breakout. [Ref]



Psychological negative effects have actually included psychological ailment (5 %), hostility (1 %), tearfulness (3 %) as well as unusual reports of depression, which has actually been one of the most usual psychological reaction to clonidine. Rare cases of frank psychoses as well as delirium have actually been associated with clonidine withdrawal. Aberrations have actually been reported postmarketing. [Ref]

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